Software

A tool to rapidly annotate genome-scale variants from large and complex functional annotation resources. VarNote is equipped by a novel index system and a parallel random-sweep searching algorithm.

A database for comprehensive and context-specific variant annotations for interpreting the molecular mechanism of genomic variations and their causal relationship with diseases/traits.

Composite machine learning models and comprehensively integrated non-coding regulatory prediction scores from existing tools for base-wise functional/pathogenic predictions of human genomic variations.

Joint likelihood framework to measure the regulatory potential of tissue/cell type-specific genetic variants.

A web-based tool to prioritize context-specific regulatory variant for human complex diseases and traits.

A database for disease/trait causal variants identified using summary statistics of genome-wide association studies.

A pipeline of summary statistics based fine-mapping using commonly-used statistical tools.

An integrative resource for quantitative trait loci across multiple human molecular phenotypes.

Fast, scalable and versatile algorithm and web tool for sampling matched sets of variants.

A deep learning model to precisely characterize the binding patterns of different types of CTCF binding sites.

Inferring cell type-specific transcriptional regulators cooperation in the context of 3D chromatin using 3D chromatin interaction and TF footprinting.

A web-based tool for comprehensive colocalization analysis by integrating large-scale and context-dependent epigenomics features.

Prediction of cancer type specificity of driver mutations via diversity spectrum analysis.

A compendium of genetic evidence that supports cardiovascular risk induced by antineoplastic drugs.

A platform for annotation and prioritization of mutations affecting drug sensitivity in cancers.

A strategy-based and disease-targeted online framework to facilitate exome sequencing studies of inherited disorders.